Chromatin structure characteristics of pre-miRNA genomic sequences
نویسندگان
چکیده
منابع مشابه
Chromatin structure analyses identify miRNA promoters.
Although microRNAs (miRNAs) are key regulators of gene expression in normal human physiology and disease, transcriptional regulation of miRNAs is poorly understood, because most miRNA promoters have not yet been characterized. We identified the proximal promoters of 175 human miRNAs by combining nucleosome mapping with chromatin signatures for promoters. We observe that one-third of intronic mi...
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MicroRNAs (miRNAs) are a class of short, non-coding RNA that play regulatory roles in a wide variety of biological processes, such as plant growth and abiotic stress responses. Although several computational tools have been developed to identify primary miRNAs and precursor miRNAs (pre-miRNAs), very few provide the functionality of locating mature miRNAs within plant pre-miRNAs. This manuscript...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2011
ISSN: 1471-2164
DOI: 10.1186/1471-2164-12-329